Dunegan L J, Tobon H, Watson C G
Surgery. 1976 Jan;79(1):57-9.
Angiosarcoma of the breast, a rare tumor with very poor prognosis and insidious early manifestations, frequently is far advanced when first detected clinically. The clinical and pathologic changes in two women with primary, unilateral angiosarcoma of the breast are reviewed and the results are compared with 46 cases already published in the literature. Both patients were middle aged with symptoms for approximately 6 months prior to operation. Both frozen section reports were benign and only called malignant on permanent section. Microscopically the tumors were composed of varying sized, tortuous, elongated vascular channels. The operation varied--a modified radical and a simple mastectomy--and both patients are free from disease 4 and 2 years following operation. It is considered that, in view of the proclivity of this tumor for hematogenous metastases, an axillary dissection may not be justified.
乳腺血管肉瘤是一种罕见肿瘤，预后极差，早期表现隐匿，临床上首次发现时往往已处于晚期。本文回顾了两名原发性单侧乳腺血管肉瘤女性患者的临床及病理变化，并将结果与文献中已发表的46例病例进行比较。两名患者均为中年，术前约有6个月的症状。两份冰冻切片报告均为良性，仅在永久切片时才诊断为恶性。显微镜下，肿瘤由大小不等、扭曲、细长的血管通道组成。手术方式不同，分别为改良根治术和单纯乳房切除术，两名患者术后4年和2年均无疾病复发。鉴于该肿瘤易于发生血行转移，认为腋窝清扫可能并无必要。
