Brandes A, Fiorentino M V
Divisione di Oncologia Medica, Azienda Ospedaliera, Padova, Italia.
Oncology. 1998 Jan-Feb;55(1):1-6. doi: 10.1159/000011827.
In recent years the elderly population has grown, and in this category there has been a marked increase in the incidence of cancers with a poor prognosis, brain tumors in particular. However, few authors have focused on treatment for high-grade gliomas in the elderly, which often present problems different from those in younger populations. Several authors have observed that this tumor has a poor response to surgery, radiotherapy and chemotherapy. Elderly patients are therefore frequently undertreated or excluded from cancer therapy trials. Their exclusion from conventional cancer treatment often depends on ad hoc decisions and assumptions by physicians rather than on sound scientific data.
近年来，老年人口不断增长，在这一群体中，预后较差的癌症发病率显著上升，尤其是脑肿瘤。然而，很少有作者关注老年高级别胶质瘤的治疗，这类肿瘤往往存在与年轻人群不同的问题。一些作者观察到，这种肿瘤对手术、放疗和化疗的反应较差。因此，老年患者常常得不到充分治疗，或被排除在癌症治疗试验之外。他们被排除在传统癌症治疗之外往往取决于医生的临时决定和假设，而非可靠的科学数据。
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