Zestos M M, Creighton R
Department of Anaesthesia and the Research Institute, Hospital for Sick Children, University of Toronto, Ontario, Canada.
Can J Anaesth. 1997 Dec;44(12):1275-7. doi: 10.1007/BF03012775.
To report intraoperative latex anaphylaxis that occurred in an otherwise healthy child. Although latex anaphylaxis is seen in patients with myelodysplasia, genitourinary anomalies, sensitised healthcare workers, and patients with frequent exposure to latex, it has not been described in otherwise healthy children.
A nine-year-old girl developed intraoperative latex anaphylaxis manifested by increased airway pressure, expiratory wheezing, a decrease in oxygen saturation, severe hypotension and urticaria. The patient was treated with 5 micrograms.kg-1 epinephrine i.v. and 5 mg.kg-1 hydrocortisone i.v. She required an epinephrine infusion of 0.4 microgram.kg-1.min-1 and prolonged ICU admission. Her only previous latex exposure was during plastic surgical procedures. Latex allergy was confirmed weeks later using the prick method allergy testing.
Latex anaphylaxis can occur in otherwise healthy children whose only latex exposure occurred during a previous operation, including plastic surgery.
报告一名原本健康的儿童术中发生乳胶过敏反应的情况。虽然在骨髓发育不良、泌尿生殖系统异常、致敏医护人员以及频繁接触乳胶的患者中可见乳胶过敏反应,但在原本健康的儿童中尚未有相关描述。
一名9岁女孩术中发生乳胶过敏反应,表现为气道压力升高、呼气性哮鸣音、氧饱和度下降、严重低血压和荨麻疹。给予患者静脉注射5微克/千克肾上腺素和5毫克/千克氢化可的松。她需要以0.4微克/千克·分钟的速度静脉输注肾上腺素,并在重症监护病房长时间住院。她之前唯一一次接触乳胶是在整形手术过程中。数周后通过点刺法过敏试验确诊为乳胶过敏。
原本健康的儿童,即使仅在之前的手术(包括整形手术)中接触过乳胶,也可能发生乳胶过敏反应。