Fagiolo E
J Immunol Methods. 1976;9(3-4):225-9. doi: 10.1016/0022-1759(76)90197-6.
The indirect anti-globulin consumption test (AGCT) with specific immunoglobulin antisera (anti-IgG and anti-IgM) has been applied to the immunochemical characterization of incomplete platelet auto-antibodies in 33 patients with idiophatic thrombocytopenic purpura (ITP), systemic lupus erythematosus (SLE) and autoimmune hemolytic anemia (AHA). In these cases indirect AGCT on platelets was positive with polyvalent gamma antiserum. The test with anti-IgG was positive in all cases except two, while always negative with anti-IgM, with no relation to the presence of complete platelet antibodies, the type of disease and the immunochemical type of erythrocyte autoantibodies in AHA patients. These results indicate that the incomplete platelets auto-antibodies were of the IgG class.
采用特异性免疫球蛋白抗血清（抗IgG和抗IgM）的间接抗球蛋白消耗试验（AGCT），已应用于33例特发性血小板减少性紫癜（ITP）、系统性红斑狼疮（SLE）和自身免疫性溶血性贫血（AHA）患者体内不完全血小板自身抗体的免疫化学特征分析。在这些病例中，用多价γ抗血清进行的血小板间接AGCT呈阳性。除两例外，抗IgG试验在所有病例中均呈阳性，而抗IgM试验始终为阴性，这与完全血小板抗体的存在、疾病类型以及AHA患者红细胞自身抗体的免疫化学类型无关。这些结果表明，不完全血小板自身抗体属于IgG类。
