Heller M, Bok D
Am J Ophthalmol. 1976 Jan;81(1):93-7. doi: 10.1016/0002-9394(76)90198-7.
By means of autoradiographic techniques the specific plasma carrier of retinol, namely retinol binding protein (RBP) in a radioactive form (retinol-125I.RBP), bound specifically in vivo to the choroidal surface of intact, isolated bovine pigment epithelial cells. The retinol-125I.RBP did not bind to the retinal surface of the pigment epithelial cells nor did not bind to photoreceptors. Retinol is normally provided to the retina from the blood via a specific complex formation with a receptor on the chordial surface of the pigment epithelial cells. Retinol metabolism might be deranged in some diseases through a defect in the pigment epithelial receptor for RBP.
通过放射自显影技术，视黄醇的特异性血浆载体，即放射性形式的视黄醇结合蛋白（RBP）（视黄醇-125I.RBP），在体内与完整的、分离的牛色素上皮细胞的脉络膜表面特异性结合。视黄醇-125I.RBP不与色素上皮细胞的视网膜表面结合，也不与光感受器结合。视黄醇通常通过与色素上皮细胞脉络膜表面的受体形成特异性复合物从血液中输送到视网膜。在某些疾病中，视黄醇代谢可能因RBP色素上皮受体缺陷而紊乱。
