Udalova L D
Arkh Anat Gistol Embriol. 1976 Jan;70(1):46-50.
It was shown that in the embryos whose fathers had been subjected to x-ray irradiation, there appeared pathological alterations involving all parts of the embryo, resulting in high postimplantation mortality. In contrast to x-ray irradiation, chloridine affecting male gametes did not result in the increased embryonic death rate and disorders in embryogenesis as compared with controls. It permitted a conclusion of the process of rat spermatogenesis being resistant to this preparation.
结果表明,在父亲受到X射线照射的胚胎中,胚胎各部位均出现病理改变,导致着床后死亡率升高。与X射线照射不同,与对照组相比,影响雄配子的氯啶并未导致胚胎死亡率增加和胚胎发育紊乱。由此可以得出结论,大鼠精子发生过程对这种制剂具有抗性。