Hayashi T, Saeki H, Takeda N, Ohko E
J Antibiot (Tokyo). 1979 Dec;32(12):1280-7. doi: 10.7164/antibiotics.32.1280.
Butirosin (Ia), 5''-amino-5''-deoxy-(Ic), 3',4'-dideoxy-(Ie), and 5''-amino-3',4',5''-trideoxy-butirosin A (If) were converted into the corresponding 1'''-deoxo derivatives, Ib, Id, Ig, and Ih by borane reduction. In addition, xylostasin (IIIa) was converted into its 1-N-ethyl derivative (IIIb) by reductive ethylation. Their antibacterial activities were discussed.
通过硼烷还原，将布替罗星（Ia）、5''-氨基-5''-脱氧布替罗星（Ic）、3',4'-二脱氧布替罗星（Ie）和5''-氨基-3',4',5''-三脱氧布替罗星A（If）转化为相应的1'''-脱氧衍生物，即Ib、Id、Ig和Ih。此外，通过还原乙基化反应，将木糖抑素（IIIa）转化为其1-N-乙基衍生物（IIIb）。并对它们的抗菌活性进行了讨论。
