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[老年患者广泛腹部手术中基于硬膜外阻滞的平衡区域麻醉]

[Balanced regional anesthesia based on epidural blockade in extensive abdominal interventions in aged patients].

作者信息

Ragozin A V, Semenichenko G G, Kozlov S P, Svetlov V A

出版信息

Anesteziol Reanimatol. 1997 Sep-Oct(5):55-9.

PMID:9432895
Abstract

A high risk of hemodynamic disorders is the main problem associated with regional blocking in elderly patients subjected to abdominal surgery. There are theoretical reasons for ganglionic blocking without hypotonus as a means preventing hemodynamic complications of regional anesthesia in traumatic interventions. Extensive operations on the abdominal organs were performed in 40 patients aged 60 to 82 years. Before surgery the epidural space at the levels from T12 to T7, depending on the level of the intervention, was catheterized. Epidural blocking was combined with drugs for intravenous anesthesia (dipidolor, diazepam, nitrogen oxide). Pentamine in a dose of 1.36 +/- 0.06 mg/kg/h and dopamine in a dose of 3 to 4 micrograms/kg/h were special component of anesthesia. Intubation of the trachea and forced ventilation of the lungs were used; myorelaxants were administered only before intubation. The intra- and postoperative periods were characterized by hemodynamic and metabolic stability and early postoperative rehabilitation. The authors consider that preventive ganglionic blocking without hypotonus attained by a combination of a dosed injection of a ganglion blocker and injection of a highly selective adrenomimetic dopamine in the microcirculation dose ensure the hemodynamic and metabolic stability of balanced anesthesia based on epidural blocking in elderly and senile patients subjected to extensive abdominal interventions. The proposed method of balanced anesthesia is an effective means of neurovegetative inhibition during epidural blocking as the basic component of anesthesia, which permits minimizing the doses of general anesthetics and ensures positive changes in the respiratory system of elderly patients, manifesting by improved pulmonary and bronchial conduction and improvement of blood gas composition.

摘要

血流动力学紊乱的高风险是老年腹部手术患者区域阻滞相关的主要问题。在创伤性干预中,无低血压的神经节阻滞作为预防区域麻醉血流动力学并发症的一种手段存在理论依据。对40例年龄在60至82岁的患者进行了腹部器官的广泛手术。术前根据手术部位,在T12至T7水平进行硬膜外腔置管。硬膜外阻滞联合静脉麻醉药物(双氯芬酸、地西泮、氧化亚氮)。麻醉的特殊组成部分是剂量为1.36±0.06mg/kg/h的喷他明和剂量为3至4μg/kg/h的多巴胺。采用气管插管和强制肺通气;仅在插管前给予肌松药。术中和术后患者血流动力学和代谢稳定,术后康复早。作者认为,通过联合给予神经节阻滞剂的定量注射和微循环剂量的高选择性拟肾上腺素多巴胺注射实现的无低血压的预防性神经节阻滞,可确保老年和高龄患者在接受广泛腹部手术时基于硬膜外阻滞的平衡麻醉的血流动力学和代谢稳定。所提出的平衡麻醉方法是硬膜外阻滞期间神经植物性抑制的有效手段,作为麻醉的基本组成部分,可使全身麻醉药剂量最小化,并确保老年患者呼吸系统的积极变化,表现为肺和支气管传导改善以及血气成分改善。

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