Polkowska J, Wolińska E, Domanski E
J Reprod Fertil. 1976 Mar;46(2):295-8. doi: 10.1530/jrf.0.0460295.
The relative proportions of prolactin cells, somatotrophs and gonadotrophs were determined in the adenohypophyses of 28 Merino ewes on selected days during the oestrous cycle. Plasma prolactin levels were measured in 16 of the animals at 3-hr intervals during the 24 hr before autopsy. From Days 1 to 5 of the cycle (Day 0=day of ovulation), plasma prolactin levels were 20-40 ng/ml and the prolactin cells were filled with granules. Plasma levels increased to 168 ng/ml between Days 6 and 9, and marked degranulation of the prolactin cells occurred. The greatest degranulation was found on Days 16 and 0, and was associated with a prolactin surge to a concentration of 610 ng/ml. The rise in plasma prolactin and intensive degranulation of prolactin cells at the time of ovulation and formation of the CL suggest that prolactin is important at this stage of the oestrous cycle.
在发情周期的特定日子，测定了28只美利奴母羊腺垂体中催乳素细胞、生长激素细胞和促性腺激素细胞的相对比例。在16只动物尸检前的24小时内，每隔3小时测量一次血浆催乳素水平。在发情周期的第1至5天（第0天=排卵日），血浆催乳素水平为20 - 40 ng/ml，催乳素细胞充满颗粒。在第6至9天，血浆水平升至168 ng/ml，催乳素细胞出现明显的脱粒现象。在第16天和第0天观察到最大程度的脱粒，且与催乳素激增至610 ng/ml的浓度相关。排卵和黄体形成时血浆催乳素的升高以及催乳素细胞的强烈脱粒表明，催乳素在发情周期的这一阶段很重要。
