Fukada J, Morishita K, Komatsu K, Abe T
Department of Thoracic and Cardiovascular Surgery, Sapporo Medical University School of Medicine, Hokkaido, Japan.
Ann Thorac Surg. 1997 Dec;64(6):1678-80; discussion 1680-1. doi: 10.1016/s0003-4975(97)00852-7.
The insertion of bioprosthetic valves into the pulmonic position is not performed commonly because of uncertainty concerning the necessity and durability of such valves.
We reviewed the long-term outcome of 10 patients who underwent pulmonary valve replacement with bioprostheses between March 1985 and March 1997. A Carpentier-Edwards supraannular bioprosthesis was used in 7 patients, a Hancock II bioprosthesis was used in 2 patients, and a Carpentier-Edwards pericardial bioprosthesis was used in 1 patient. The mean patient age at the time of pulmonary valve replacement was 38.9 +/- 16.3 years (range, 15 to 63 years). The diagnoses were pulmonary valvular regurgitation after corrective surgery for tetralogy of Fallot in 7 patients, right ventricular outflow tract stenosis and absent right pulmonary artery combined with a double-outlet right ventricle in 1 patient, pulmonary valvular regurgitation with pulmonary artery dilatation in 1 patient, and aortic valve stenosis treated with our modification of the Ross procedure using a pulmonary bioprosthesis in 1 patient. Survivors were followed up for a mean of 5 years and 5 months.
One patient underwent reoperation because of infective endocarditis of the bioprosthesis. No bioprosthetic valve dysfunction has been observed on Doppler echocardiography during a maximum follow-up period of 12.2 years, except in the patient who underwent replacement at 15 years of age.
Bioprostheses in the pulmonic position are durable in adult patients because they face a minimal hemodynamic load, but they may undergo early leaflet degeneration in younger patients.
由于生物瓣膜用于肺动脉位置的必要性和耐久性存在不确定性,故其植入并不常见。
我们回顾了1985年3月至1997年3月期间接受生物瓣膜肺动脉瓣置换术的10例患者的长期预后。7例患者使用Carpentier-Edwards瓣环上生物瓣膜,2例患者使用Hancock II生物瓣膜,1例患者使用Carpentier-Edwards心包生物瓣膜。肺动脉瓣置换时患者的平均年龄为38.9±16.3岁(范围15至63岁)。诊断包括:7例法洛四联症矫正术后肺动脉瓣反流;1例右心室流出道狭窄、右肺动脉缺如合并右心室双出口;1例肺动脉瓣反流合并肺动脉扩张;1例主动脉瓣狭窄采用改良Ross手术并使用肺动脉生物瓣膜治疗。对存活患者平均随访5年零5个月。
1例患者因生物瓣膜感染性心内膜炎接受再次手术。除15岁接受置换的患者外,在最长12.2年的随访期内,多普勒超声心动图未观察到生物瓣膜功能障碍。
生物瓣膜用于肺动脉位置在成年患者中耐久性良好,因为其承受的血流动力学负荷最小,但在年轻患者中可能会出现早期瓣叶退变。