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肺动脉位置对生物人工心脏瓣膜耐久性的影响。

Influence of pulmonic position on durability of bioprosthetic heart valves.

作者信息

Fukada J, Morishita K, Komatsu K, Abe T

机构信息

Department of Thoracic and Cardiovascular Surgery, Sapporo Medical University School of Medicine, Hokkaido, Japan.

出版信息

Ann Thorac Surg. 1997 Dec;64(6):1678-80; discussion 1680-1. doi: 10.1016/s0003-4975(97)00852-7.

Abstract

BACKGROUND

The insertion of bioprosthetic valves into the pulmonic position is not performed commonly because of uncertainty concerning the necessity and durability of such valves.

METHODS

We reviewed the long-term outcome of 10 patients who underwent pulmonary valve replacement with bioprostheses between March 1985 and March 1997. A Carpentier-Edwards supraannular bioprosthesis was used in 7 patients, a Hancock II bioprosthesis was used in 2 patients, and a Carpentier-Edwards pericardial bioprosthesis was used in 1 patient. The mean patient age at the time of pulmonary valve replacement was 38.9 +/- 16.3 years (range, 15 to 63 years). The diagnoses were pulmonary valvular regurgitation after corrective surgery for tetralogy of Fallot in 7 patients, right ventricular outflow tract stenosis and absent right pulmonary artery combined with a double-outlet right ventricle in 1 patient, pulmonary valvular regurgitation with pulmonary artery dilatation in 1 patient, and aortic valve stenosis treated with our modification of the Ross procedure using a pulmonary bioprosthesis in 1 patient. Survivors were followed up for a mean of 5 years and 5 months.

RESULTS

One patient underwent reoperation because of infective endocarditis of the bioprosthesis. No bioprosthetic valve dysfunction has been observed on Doppler echocardiography during a maximum follow-up period of 12.2 years, except in the patient who underwent replacement at 15 years of age.

CONCLUSIONS

Bioprostheses in the pulmonic position are durable in adult patients because they face a minimal hemodynamic load, but they may undergo early leaflet degeneration in younger patients.

摘要

背景

由于生物瓣膜用于肺动脉位置的必要性和耐久性存在不确定性,故其植入并不常见。

方法

我们回顾了1985年3月至1997年3月期间接受生物瓣膜肺动脉瓣置换术的10例患者的长期预后。7例患者使用Carpentier-Edwards瓣环上生物瓣膜,2例患者使用Hancock II生物瓣膜,1例患者使用Carpentier-Edwards心包生物瓣膜。肺动脉瓣置换时患者的平均年龄为38.9±16.3岁(范围15至63岁)。诊断包括:7例法洛四联症矫正术后肺动脉瓣反流;1例右心室流出道狭窄、右肺动脉缺如合并右心室双出口;1例肺动脉瓣反流合并肺动脉扩张;1例主动脉瓣狭窄采用改良Ross手术并使用肺动脉生物瓣膜治疗。对存活患者平均随访5年零5个月。

结果

1例患者因生物瓣膜感染性心内膜炎接受再次手术。除15岁接受置换的患者外,在最长12.2年的随访期内,多普勒超声心动图未观察到生物瓣膜功能障碍。

结论

生物瓣膜用于肺动脉位置在成年患者中耐久性良好,因为其承受的血流动力学负荷最小,但在年轻患者中可能会出现早期瓣叶退变。

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