Abercrombie J F, Rogers J, Swash M
Surgical Unit, The Royal London Hospital, UK.
J Neurol Neurosurg Psychiatry. 1998 Jan;64(1):128-30. doi: 10.1136/jnnp.64.1.128.
Two siblings with myotonic dystrophy presented for treatment of faecal incontinence. The pathophysiology of this functional disorder is described with the results of anorectal manometry, EMG, and biopsy of smooth and striated muscle of the anorectal sphincters. Both medical and surgical management of the incontinence was unsatisfactory in the long term. Involvement of gastrointestinal musculature is a characteristic feature the disease.
两名患有强直性肌营养不良症的兄弟姐妹因大便失禁前来接受治疗。本文结合肛门直肠测压、肌电图以及肛门直肠括约肌平滑肌和横纹肌活检结果，描述了这种功能性障碍的病理生理学。从长期来看，失禁的药物治疗和手术治疗效果均不理想。胃肠道肌肉组织受累是该疾病的一个特征。
