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小梁骨研究中计算机模拟与体模测量相位方差的比较

Comparison of computer simulated and phantom measured phase variance in the study of trabecular bone.

作者信息

Mihalopoulou E, Allein S, Luypaert R, Eisendrath H, Bezerianos A, Panayiotakis G

机构信息

Department of Medical Physics, School of Medicine, University of Patras, Greece.

出版信息

Magn Reson Imaging. 1998;16(1):29-36. doi: 10.1016/s0730-725x(97)00218-x.

DOI:10.1016/s0730-725x(97)00218-x
PMID:9436944
Abstract

A new method using magnetic resonance phase images for the assessment of trabecular bone structure has recently been proposed. To test this method, a mathematical model is developed which calculates the phase distribution in gradient echo acquired phase images of a structure of Pyrex glass rods immersed in a copper sulfate solution. Several experiments were performed using a phantom built in the same way as the structure used in the mathematical model. The results from the model are compared with those from the phantom tests, and the influence of resolution and bone area fraction on the phase dispersion is studied. The good correlation between theoretical and experimental results shows that phase variance increases with increasing resolution and bone density. However, the dependence of variance on bone density is less prominent for large pixel sizes.

摘要

最近提出了一种利用磁共振相位图像评估小梁骨结构的新方法。为了测试该方法,开发了一个数学模型,该模型计算浸没在硫酸铜溶液中的派热克斯玻璃棒结构的梯度回波采集相位图像中的相位分布。使用以与数学模型中使用的结构相同的方式构建的体模进行了多项实验。将模型结果与体模测试结果进行比较,并研究分辨率和骨面积分数对相位色散的影响。理论结果与实验结果之间的良好相关性表明,相位方差随分辨率和骨密度的增加而增加。然而,对于大像素尺寸,方差对骨密度的依赖性不太明显。

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Comparison of computer simulated and phantom measured phase variance in the study of trabecular bone.小梁骨研究中计算机模拟与体模测量相位方差的比较
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