Emeryk B, Rubach K, Barcikowski B, Kwiatkowska Z
Neurol Neurochir Pol. 1976 Jan-Feb;10(1):25-30.
In a group of 31 women with myasthenia the urinary excretion of 17-ketosteroids and their fractions (11-deoxy-17-ketosteroids, dehydroisoandrosterone) and 17-hydroxycorticosterone were determined. A statistically significant decrease was observed in the excretion of these substances. Besides that, the plasma cortisol level was determined in these patients and the results obtained in the whole group were at the lower normal range of the laboratory and in 40% of cases they were significantly lower (p less than 0.01). The obtained results may suggest that adrenocortical hypofunction exists in many cases of myasthenia. The pertinent literature is reviewed.
对31名重症肌无力女性患者测定了17-酮类固醇及其组分（11-脱氧-17-酮类固醇、脱氢异雄酮）以及17-羟皮质酮的尿排泄量。观察到这些物质的排泄量有统计学意义的下降。除此之外，还测定了这些患者的血浆皮质醇水平，全组结果处于实验室正常范围下限，40%的病例明显更低（p<0.01）。所得结果可能提示在许多重症肌无力病例中存在肾上腺皮质功能减退。对相关文献进行了综述。
