Rizzetto M, Bigo A, Pinna G, Barbando G
Minerva Med. 1976 Feb 11;67(7):433-42.
Six cases of pseudomembranous colitis caused by antibiotics are presented. The endoscopic, radiological and clinical picture and the aetiopathogenesis of this unusual disease are discussed. Lincomycin was incriminated in one case only. In the remainder, various antibiotics of different chemical structure were responsible. Carcinoma of the colon was a common feature and it is suggested that a full examination of the large intestine should be made whenever this syndrome appears. While radiological suspicion may be forthcoming, pseudomembranous colitis is diagnosed only by endoscopy and biopsy.
本文报告了6例由抗生素引起的伪膜性结肠炎。讨论了这种罕见疾病的内镜、放射学和临床特征以及病因发病机制。仅1例病因归咎于林可霉素。其余病例则由各种化学结构不同的抗生素所致。结肠癌是一个常见特征,建议每当出现该综合征时,都应对大肠进行全面检查。虽然可能会出现放射学怀疑,但伪膜性结肠炎仅通过内镜检查和活检来诊断。