Inglot A D
Laboratory of Virology, Polish Academy of Sciences, Wrocław, Poland.
Arch Immunol Ther Exp (Warsz). 1997;45(5-6):353-7.
A simple classification of cytokines is presented. It is based on voluminous information available from published papers of many outstanding researchers of the cytokines and their receptors and/or summarized by experts in this field. The cytokines are divided into 7 families according to their receptor code. Such arrangement of apparently different cytokines may explain the biological significance of pleiotropy and redundancy. Furthermore, it may stimulate the development of the comprehensive classification of cytokines together with classical hormones, neuromediators, neuromodulators and related substances that participate in complex biological communication system.
本文给出了细胞因子的一种简单分类。它基于众多杰出的细胞因子及其受体研究人员发表的论文中所提供的大量信息，或由该领域专家总结而成。根据其受体编码，细胞因子被分为7个家族。这种对明显不同的细胞因子的排列方式可能解释了多效性和冗余性的生物学意义。此外，它可能会促进细胞因子与经典激素、神经介质、神经调节剂以及参与复杂生物通讯系统的相关物质的综合分类的发展。
