Monzón-Mayor M, Yanes C, De Barry J, Capdevilla-Carbonell C, Renau-Piqueras J, Tholey G, Gombos G
Departamento de Morfología, Facultad de Ciencias de la Salud, Universidad de Las Palmas de G.C., Canary Islands, Spain.
J Morphol. 1998 Feb;235(2):109-19. doi: 10.1002/(SICI)1097-4687(199802)235:2<109::AID-JMOR2>3.0.CO;2-4.
Astrocytes and radial glia coexist in the adult mesencephalon of the lizard Gallotia galloti. Radial glia and star-shaped astrocytes express glial fibrillary acidic protein (GFAP) and glutamine synthetase (GS). The same cell markers are also expressed by round or pear-shaped cells that are therefore astrocytes with unusual morphology. Other round or pear-shaped cells, also scattered in the tegmentum and the tectum, display only GS. Electron microscopy reveals that these cells may be oligodendrocytes. In this lizard, the GS is expressed in some oligodendrocytes while this does not occur in the central nervous system of mammals in situ. These results confirm that the cellular specificity of GS is different in various species and suggest that ependymal cells are also immunoreactive for GS but they do not contain GFAP.
星形胶质细胞和放射状胶质细胞共存于加那利蜥蜴（Gallotia galloti）的成体中脑。放射状胶质细胞和星形胶质细胞表达胶质纤维酸性蛋白（GFAP）和谷氨酰胺合成酶（GS）。同样的细胞标志物也由圆形或梨形细胞表达，因此这些细胞是形态异常的星形胶质细胞。其他同样散布在被盖和顶盖中的圆形或梨形细胞仅表达GS。电子显微镜显示这些细胞可能是少突胶质细胞。在这种蜥蜴中，GS在一些少突胶质细胞中表达，而在哺乳动物中枢神经系统原位则不表达。这些结果证实GS的细胞特异性在不同物种中有所不同，并表明室管膜细胞对GS也有免疫反应，但它们不含有GFAP。
