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果蝇中宿主在调控转座元件活性方面作用的证据:以夏洛尔品系中Bari 1元件的持续不稳定性为例

Evidence for a host role in regulating the activity of transposable elements in Drosophila melanogaster: the case of the persistent instability of Bari 1 elements in Charolles stock.

作者信息

Junakovic N, Di Franco C, Terrinoni A

机构信息

Centro per lo Studio degli Acidi Nucleici C.N.R., Roma, Italy.

出版信息

Genetica. 1997;100(1-3):149-54.

PMID:9440267
Abstract

In most reports in which the activity of numerous Drosophila transposon families has been studied, only a subset of the families tested appears mobile. A comparison of these data shows that there are no transposons inherently more unstable than others and suggests that host factors regulate the activity of transposable elements. Consistent with this conclusion are the properties of Bari 1 elements, which are the only ones of the 14 families tested to be unstable in Charolles stock. Instability is persistent over 53 generations and appears to affect recurrent insertion sites.

摘要

在大多数研究众多果蝇转座子家族活性的报告中,所测试的家族中只有一部分似乎具有移动性。对这些数据的比较表明,不存在本质上比其他转座子更不稳定的转座子,这表明宿主因子调节转座元件的活性。Bari 1元件的特性与这一结论一致,在夏罗勒品系中,Bari 1元件是所测试的14个家族中唯一不稳定的元件。这种不稳定性在53代中持续存在,并且似乎影响重复插入位点。

相似文献

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Evidence for a host role in regulating the activity of transposable elements in Drosophila melanogaster: the case of the persistent instability of Bari 1 elements in Charolles stock.果蝇中宿主在调控转座元件活性方面作用的证据:以夏洛尔品系中Bari 1元件的持续不稳定性为例
Genetica. 1997;100(1-3):149-54.
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Conserved motifs and dynamic aspects of the terminal inverted repeat organization within Bari-like transposons.类Bari转座子内末端反向重复序列组织的保守基序和动态特征。
Mol Genet Genomics. 2008 May;279(5):451-61. doi: 10.1007/s00438-008-0324-7.
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