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心脏手术后意外心脏骤停:开胸心肺复苏的发生率、诱发原因及结果

Unexpected cardiac arrest after cardiac surgery: incidence, predisposing causes, and outcome of open chest cardiopulmonary resuscitation.

作者信息

Anthi A, Tzelepis G E, Alivizatos P, Michalis A, Palatianos G M, Geroulanos S

机构信息

Surgical Intensive Care Unit, Onassis Cardiac Surgical Center, Athens, Greece.

出版信息

Chest. 1998 Jan;113(1):15-9. doi: 10.1378/chest.113.1.15.

DOI:10.1378/chest.113.1.15
PMID:9440561
Abstract

STUDY OBJECTIVES

To assess the incidence of acute mechanical causes precipitating sudden cardiac arrest in cardiac surgery patients during the immediate postoperative period. In addition, we report the success rate of cardiopulmonary resuscitation (CPR) in which open-chest CPR was employed at an early stage of the resuscitation effort.

METHODS

Data on all cardiac surgical patients who suffered a sudden cardiac arrest during the first 24 h after surgery were collected prospectively. CPR consisted of conventional closed-chest CPR initially and was followed within 3 to 5 min, if needed, by open-chest CPR.

RESULTS

Of 3,982 patients undergoing cardiac surgery over a 30-month period, 29 patients (0.7%) had a sudden cardiac arrest. Of these, 13 patients (45%) were successfully resuscitated with closed-chest CPR, 14 (48%) with open-chest CPR, and 2 (7%) died despite closed- and open-chest CPR. Four CPR survivors died subsequently in the ICU, yielding an overall hospital discharge rate of 79%. Perioperative myocardial infarction was the underlying cause of sudden cardiac arrest in 14 patients (48%), and mechanical impediments to cardiac function (tamponade or graft malfunction) in another 8 (28%) patients; in the remaining 7 patients (24%), no underlying cause was found. The length of ICU stay was 6+/-1 (mean+/-SE) days. None of the patients developed wound infection and all were neurologically intact at hospital discharge.

CONCLUSION

Mechanical factors account for a substantial portion (28%) of causes of sudden cardiac arrest occurring in hemodynamically stable patients during the immediate postoperative period. This high incidence, in conjunction with the high survival rate achieved by open CPR, supports an early approach to open-chest CPR in this group of patients.

摘要

研究目的

评估心脏手术患者术后早期急性机械性病因引发心脏骤停的发生率。此外,我们报告了在复苏早期采用开胸心肺复苏术(CPR)的心肺复苏成功率。

方法

前瞻性收集所有术后24小时内发生心脏骤停的心脏手术患者的数据。CPR最初包括传统的闭胸CPR,如有需要,在3至5分钟内转为开胸CPR。

结果

在30个月期间接受心脏手术的3982例患者中,29例(0.7%)发生心脏骤停。其中,13例(45%)通过闭胸CPR成功复苏,14例(48%)通过开胸CPR成功复苏,2例(7%)尽管接受了闭胸和开胸CPR仍死亡。4例CPR幸存者随后在重症监护病房(ICU)死亡,总体出院率为79%。围手术期心肌梗死是14例(48%)心脏骤停的根本原因,另有8例(28%)患者存在心脏功能的机械性障碍(心包填塞或移植物功能障碍);其余7例(24%)未发现根本原因。ICU住院时间为6±1(平均±标准误)天。所有患者均未发生伤口感染,出院时神经功能均完好。

结论

机械因素占术后早期血流动力学稳定患者心脏骤停原因的很大一部分(28%)。这一高发生率,结合开胸CPR所取得的高生存率,支持对这组患者尽早采用开胸CPR。

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