Freund M, Hutzelmann A, Steffens J C, Buhl R, Heller M
Klinik für Radiologische Diagnostik, Christian-Albrechts-Universität zu Kiel.
Rofo. 1997 Nov;167(5):474-8. doi: 10.1055/s-2007-1015566.
The purpose of this prospective study was to evaluate the clinical value of 3D-MR-myelography (3D-MRM) in comparison to myelography and intra-operative findings.
25 patients with suspected lumbar spinal canal stenosis were studied via myelography and 3D-MRM (volume-data set, 3D-FISP sequence, TR 73 ms, TE 21 ms, flip angle 7 degrees, sagittal slices) besides the routinely acquired sagittal and axial T1- and T2-weighted images. Diagnoses were made by two radiologists and one neurosurgeon without knowing the clinical history and symptoms, in two separate sessions. Results were compared to intraoperative findings.
3D-MRM has the same diagnostic sensitivity (25/25 = 100%) as conventional X-ray myelography (25/25 = 100%) compared to intraoperative findings, but is not invasive and shows more diagnostic details than myelography. Especially in cases of high-grade spinal canal stenosis there is often a lack of intrathecal contrast medium distally of the stenosis.
3D-MRM is as good as conventional myelography in predicting intraoperative findings in patients with lumbar spinal canal stenosis. This new method is non-invasive and can be performed routinely on an outpatient basis.
本前瞻性研究旨在评估三维磁共振脊髓造影(3D-MRM)相较于脊髓造影及术中所见的临床价值。
除常规获取的矢状位和轴位T1加权及T2加权图像外,对25例疑似腰椎管狭窄患者进行了脊髓造影及3D-MRM检查(容积数据集,3D-FISP序列,TR 73毫秒,TE 21毫秒,翻转角7度,矢状位切片)。由两位放射科医生和一位神经外科医生在不了解临床病史和症状的情况下,分两次独立做出诊断。将结果与术中所见进行比较。
与术中所见相比,3D-MRM与传统X线脊髓造影具有相同的诊断敏感性(25/25 = 100%),但它是非侵入性的,且比脊髓造影显示出更多的诊断细节。特别是在重度椎管狭窄病例中,狭窄远端常常缺乏鞘内造影剂。
在预测腰椎管狭窄患者的术中所见方面,3D-MRM与传统脊髓造影效果相当。这种新方法是非侵入性的,可作为门诊常规检查。