Beyersdorf F, van de Loo A
Abteilung Herz- und Gefässchirurgie, Herz-Kreislauf-Zentrum des Klinikums der Albert-Ludwigs-Universität Freiburg.
Herz. 1997 Oct;22(5):272-6. doi: 10.1007/BF03044255.
Congestive heart failure is a clinical condition with a high mortality. Medical therapy has improved the clinical course of these patients considerably in recent years. Numerous surgical interventions such as high risk coronary bypass surgery, resection of left ventricular aneurysms, heart valve replacement and cardiac transplantation became accepted therapeutical options. More recently, transmyocardial laser revascularization, implantation of mechanical assist devices, implantable cardioverters/defibrillators and dynamic cardiomyoplasty were introduced into clinical practice and are still under evaluation. For most patients suffering from congestive heart failure cardiac transplantation is the only therapeutical option. However, age of the patients, decreasing number of donors, mortality on the waiting list, high morbidity under immunosuppressive therapy and graft vasculopathy characterize the problems of this therapeutical strategy. The brasilian cardiac surgeon Randas Batista therefore has introduced a new organ preserving surgical technique. First reports on "partial left ventricular resection" for patients with end-stage cardiac failure and dilated ventricles are promising. The possible importance of this new surgical technique implies that precise clinical and scientific evaluation are imperatively needed. In this review we present the surgical procedure, published data on clinical outcome and hemodynamic changes and possible indications for this new technique. The few data which have been published so far might indicate that there is an acceptable perioperative mortality associated with a symptomatic improvement. However, intermediate and long-term follow-up data are not available, and refinements in the surgical technique are necessary.
充血性心力衰竭是一种死亡率很高的临床病症。近年来,药物治疗已显著改善了这些患者的临床病程。许多外科手术干预,如高风险冠状动脉搭桥手术、左心室动脉瘤切除术、心脏瓣膜置换术和心脏移植术,已成为公认的治疗选择。最近,经心肌激光血运重建术、机械辅助装置植入术、植入式心脏复律除颤器和动力性心肌成形术已应用于临床实践,目前仍在评估中。对于大多数充血性心力衰竭患者来说,心脏移植是唯一的治疗选择。然而,患者的年龄、供体数量的减少、等待名单上的死亡率、免疫抑制治疗下的高发病率以及移植物血管病变是这种治疗策略所面临的问题。因此,巴西心脏外科医生兰达斯·巴蒂斯塔引入了一种新的保留器官的手术技术。关于终末期心力衰竭和心室扩张患者的“部分左心室切除术”的初步报告很有前景。这种新手术技术的潜在重要性意味着迫切需要进行精确的临床和科学评估。在这篇综述中,我们介绍了手术过程、已发表的关于临床结果和血流动力学变化的数据以及这种新技术的可能适应症。到目前为止已发表的少量数据可能表明,围手术期死亡率在可接受范围内,且症状有所改善。然而,缺乏中期和长期随访数据,手术技术的改进是必要的。