Gómez de la Cámara A
Fondo de Investigación Sanitaria, Red Estatal de Unidades de Investigación (REUNI), Madrid.
Med Clin (Barc). 1997 Oct 11;109(12):445-51.
Currently the methodological features of the applied-research grant proposals submitted to the Research Agencies are not well known while they play an important role in the evaluation process. The objectives of this work were to describe the methodological features and appropriateness in the fulfillment of a sample of proposals submitted to the Fondo de Investigación Sanitaria (FIS).
216 proposals submitted to the FIS in 1993 and 1994. A specific revision protocol was designed to assess the objectives of the study according with criteria drown from the scientific literature.
Most of the proposals correctly fulfill the items relative to the research problem description and justification. The operative component of the scientific method is scarcely fulfilled in the proposal hypothesis, objectives and methods. A 30% of the proposals do not show a typical research frame. The observational design and the basic field research are the most frequent findings in their items. The study variables, subjects, information management, plan of analysis and organization are incomplete or wrong filled in more than 50% of the proposals. The accepted proposals had an score of 1.93 in the degree of appropriate fulfillment and the non accepted 1.76, p = 0.001. The item with the strongest association to the acceptation was the appropriate definition of the variables, OR = 21.6 (CI 95%: 4.90-45.7).
The methodological structure is not appropriate in more than 50% of the proposals submitted to the FIS. The appropriateness in the fulfillment of the methodological features increase the probability of their acceptance.
目前，提交给研究机构的应用研究资助提案的方法学特征尚不为人所知，然而它们在评估过程中发挥着重要作用。这项工作的目的是描述提交给卫生研究基金（FIS）的一组提案样本的方法学特征及其在完成情况方面的适宜性。
1993年和1994年提交给FIS的216份提案。设计了一个特定的审查方案，以根据从科学文献中得出的标准评估研究目标。
大多数提案正确地完成了与研究问题描述和论证相关的项目。科学方法的操作部分在提案的假设、目标和方法中几乎没有得到体现。30%的提案没有呈现出典型的研究框架。观察性设计和基础实地研究是其项目中最常见的情况。在超过50%的提案中，研究变量、研究对象、信息管理、分析计划和组织部分填写不完整或有误。被接受的提案在适宜完成程度方面的得分为1.93，未被接受的为1.76，p = 0.001。与接受情况关联最强的项目是变量的恰当定义，比值比（OR）= 21.6（95%置信区间：4.90 - 45.7）。
提交给FIS的提案中，超过50%的提案方法学结构不合适。方法学特征完成情况的适宜性增加了提案被接受的可能性。
