Bahlmann F, Merz E, Weber G, Wellek S, Engelhardt O
Universitäts-Frauenklinik Mainz.
Ultraschall Med. 1997 Oct;18(5):196-204. doi: 10.1055/s-2007-1000425.
Evaluation of a growth model for the biometric parameters of early pregnancy: Chorionic cavity, yolk sac, amniotic cavity, crown-rump length and biparietal diameter.
618 clinically well-dated singleton pregnancies of the first trimester were measured in a prospective cross-sectional study with high-frequency transvaginal ultrasound between 28 and 94 days post menstruation.
Normal curves (5th, 50th, 95th percentiles) for all parameters were established using our growth model. The growth curves of chorionic cavity amniotic cavity, and biparietal diameter showed a linear growth whereas the growth curve of the crown-rump-length represented an exponential curve. Linear growth of the yolk sac was found until 8 weeks of gestation and there was no growth alteration after this time.
With our growth curves of the first trimester it is possible to monitor the embryonic development with several parameters.
评估孕早期生物测量参数的生长模型：绒毛膜腔、卵黄囊、羊膜腔、头臀长度和双顶径。
在一项前瞻性横断面研究中，对618例月经周期正常的孕早期单胎妊娠进行了测量，测量时间为月经后28至94天，采用高频经阴道超声检查。
使用我们的生长模型建立了所有参数的正常曲线（第5、50、95百分位数）。绒毛膜腔、羊膜腔和双顶径的生长曲线呈线性增长，而头臀长度的生长曲线呈指数曲线。卵黄囊在妊娠8周前呈线性生长，此后无生长变化。
利用我们的孕早期生长曲线，可以通过多个参数监测胚胎发育情况。
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