Konje J C, Abrams K R, Bell S C, Taylor D J
Fetal Growth and Development Research Group, Department of Obstetrics and Gynaecology, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, UK.
Ultrasound Obstet Gynecol. 2002 Jun;19(6):592-7. doi: 10.1046/j.1469-0705.2002.00704.x.
To evaluate the application of kidney length measurement to the determination of gestational age between the 24th and 38th weeks and to compare its accuracy with that of other fetal biometric indices.
Seventy-three women with singleton uncomplicated pregnancies underwent standard ultrasound fetal biometry and kidney length measurement every 2 weeks between 24 and 38 weeks' gestation. These measurements were used to date the pregnancies relative to crown-rump length dating between 8 and 10 weeks' gestation. Linear regression models for estimation of gestational age were derived from the biometric indices and kidney length. In addition, stepwise regression models were constructed to determine the best model for determining gestational age between 24 and 38 weeks. Comparisons were then made between the accuracy of these models in the determination of gestational age.
The best model for estimating gestational age in late pregnancy included the variables kidney length, biparietal diameter, head circumference, femur length and abdominal circumference. This model accurately predicted gestational age with a standard error of +/- 8.48 days. A model including kidney length, biparietal diameter, head circumference and femur length accurately predicted gestational age with a standard error of +/- 8.57 days. These models were slightly more accurate than models derived from the biometric indices of biparietal diameter, head circumference and femur length (+/- 9.87 days), biparietal diameter, head circumference, femur length and abdominal circumference (+/- 9.45 days) and biparietal diameter and femur length (+/- 9.9 days). Kidney length and femur length were the most accurate single parameters for predicting gestational age using simple linear regression models (+/- 10.29 and 10.96 days, respectively); the abdominal circumference was the least accurate (+/- 14.54 days).
Kidney length is a more accurate method of determining gestational age than the fetal biometric indices of biparietal diameter, head circumference, femur length and abdominal circumference between 24 and 38 weeks' gestation. When combined with biparietal diameter, head circumference and femur length, the precision of dating is improved by 2 days. This measurement is easy to make and could therefore be easily incorporated into the model for dating pregnancies after 24 weeks of gestation, in particular when measurements of the biparietal diameter and head circumference are difficult.
评估肾长测量在孕24至38周确定孕周中的应用，并将其准确性与其他胎儿生物测量指标的准确性进行比较。
73名单胎无并发症妊娠的女性在妊娠24至38周期间每2周接受一次标准超声胎儿生物测量和肾长测量。这些测量用于确定相对于妊娠8至10周时头臀长测量的孕周。从生物测量指标和肾长得出估计孕周的线性回归模型。此外，构建逐步回归模型以确定孕24至38周确定孕周的最佳模型。然后对这些模型在确定孕周方面的准确性进行比较。
孕晚期估计孕周的最佳模型包括肾长、双顶径、头围、股骨长和腹围这些变量。该模型准确预测孕周，标准误差为±8.48天。一个包括肾长、双顶径、头围和股骨长的模型准确预测孕周，标准误差为±8.57天。这些模型比从双顶径、头围和股骨长（±9.87天）、双顶径、头围、股骨长和腹围（±9.45天）以及双顶径和股骨长（±9.9天）的生物测量指标得出的模型略准确。使用简单线性回归模型时，肾长和股骨长是预测孕周最准确的单一参数（分别为±10.29和10.96天）；腹围最不准确（±14.54天）。
在妊娠24至38周期间，肾长是一种比双顶径、头围、股骨长和腹围的胎儿生物测量指标更准确的确定孕周的方法。当与双顶径、头围和股骨长结合时，孕周确定的精度提高2天。该测量易于进行，因此可以很容易地纳入妊娠24周后确定孕周的模型中，特别是在双顶径和头围测量困难时。
