Nerheim O O, Freng A, Sauer T
Ore-nese-halsavdelingen, Ullevål sykehus, Oslo.
Tidsskr Nor Laegeforen. 1997 Nov 20;117(28):4074-6.
Tumours in the large salivary glands i.e. glandula submandibularis and glandula parotis are easily accessible by fine needle aspiration. Because of the great variation in morphology, diagnosis is difficult and requires a high level of experience. In this study, which lasted for 4.5 years, 343 fine needle aspiration were carried out on 343 patients. Cytological diagnoses were made in 336 lesions and histological diagnosis in 113. Four false positives and one false negative resulted in a sensitivity of 96.9% and a specificity of 95.3% with respect to malignancy. All aspirations were carried out by experienced cytopathologists, in close cooperation with an attendant ear, nose and throat specialist.
大唾液腺(即下颌下腺和腮腺)中的肿瘤可通过细针穿刺轻易获取样本。由于其形态差异极大,诊断困难,需要高水平的经验。在这项持续4.5年的研究中,对343例患者进行了343次细针穿刺。对336个病变进行了细胞学诊断,113个进行了组织学诊断。4例假阳性和1例假阴性导致对恶性肿瘤的敏感性为96.9%,特异性为95.3%。所有穿刺均由经验丰富的细胞病理学家在与耳鼻喉专科医生密切合作下进行。