Mekler G, Woggon B
Psychiatric University Hospital, Zurich, Switzerland.
Pharmacopsychiatry. 1997 Nov;30(6):272-3. doi: 10.1055/s-2007-979507.
Serotonin syndrome occurred under treatment with average dose of Venlafaxine and lithium in a 50 year-old female patient with a history of sensitiveness to SSRIs. Plasma levels of Venlafaxine and its metabolite were within reference range. Parmacogenetic evaluation indicated normal metabolic pathway.
一名有SSRI类药物敏感史的50岁女性患者,在接受平均剂量的文拉法辛和锂治疗时发生了血清素综合征。文拉法辛及其代谢物的血浆水平在参考范围内。药物遗传学评估表明代谢途径正常。