帕金森病

Parkinson's disease.

作者信息

Barbosa E R, Limongi J C, Cummings J L

机构信息

Department of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.

出版信息

Psychiatr Clin North Am. 1997 Dec;20(4):769-90. doi: 10.1016/s0193-953x(05)70344-0.

DOI:10.1016/s0193-953x(05)70344-0

PMID:9443349

Abstract

Parkinson's disease (PD) is one of the most common neurodegenerative diseases and affects 150 to 200 people per 100,000 population. Rapid advances have been made in the neurobiology of PD; this disorder is now recognized as a model of dysfunction in fronto-striatal circuits expressed by motor and behavioral symptoms. Several clinical and surgical strategies for the management of PD are discussed.

摘要

帕金森病（PD）是最常见的神经退行性疾病之一，每10万人中有150至200人受其影响。帕金森病的神经生物学研究取得了快速进展；这种疾病现在被认为是一种由运动和行为症状所表现出的额颞叶回路功能障碍模型。本文讨论了几种治疗帕金森病的临床和手术策略。