Haddad M S, Cummings J L
Department of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
Psychiatr Clin North Am. 1997 Dec;20(4):791-807. doi: 10.1016/s0193-953x(05)70345-2.
Huntington's disease is a genetically inherited degenerative neuropsychiatric disorder, characterized by motor alterations, including involuntary movements such as chorea, dementia and psychiatric disturbances. In this article, the authors review the clinical features of the disease. They also analyze some genetic and pathophysiologic aspects, that can help to improve our understanding of this disorder involving the basal ganglia.
亨廷顿舞蹈症是一种遗传性神经退行性精神疾病，其特征为运动改变，包括舞蹈样不自主运动、痴呆和精神障碍。在本文中，作者回顾了该疾病的临床特征。他们还分析了一些遗传和病理生理学方面的内容，这有助于增进我们对这种累及基底神经节的疾病的理解。
