Cardoso F, Jankovic J
Department of Neurology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Psychiatr Clin North Am. 1997 Dec;20(4):821-38. doi: 10.1016/s0193-953x(05)70347-6.
Dystonia is defined as a syndrome of sustained muscle contractions, frequently causing twisting and repetitive movements, or abnormal postures. Tardive dyskinesia (TD), estimated to occur in 30% of patients treated with neuroleptics, encompasses a broad spectrum of hyperkinesias associated with exposure to these drugs. Dystonia is one of the most common expressions of tardive dyskinesia. This article aims to provide an overview of classification, phenomenology, epidemiology, genetics, pathophysiology, neuropsychologic aspects, and treatment of these two conditions.
肌张力障碍被定义为一种持续肌肉收缩的综合征,常导致扭曲和重复性动作,或异常姿势。迟发性运动障碍(TD)估计发生在30%接受抗精神病药物治疗的患者中,包括与接触这些药物相关的广泛运动亢进。肌张力障碍是迟发性运动障碍最常见的表现之一。本文旨在概述这两种病症的分类、现象学、流行病学、遗传学、病理生理学、神经心理学方面及治疗。