Busatto G F, Kerwin R W
Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo, Brazil.
Psychiatr Clin North Am. 1997 Dec;20(4):897-910. doi: 10.1016/s0193-953x(05)70351-8.
Schizophrenia is one of the most common and perhaps the most disabling of mental disorders, for which effective forms of treatment have not yet been established definitively. The findings reviewed in this article strongly suggest that basal ganglia abnormalities are involved in the pathophysiology of psychotic syndromes in general, and schizophrenia in particular.
精神分裂症是最常见且可能是最具致残性的精神障碍之一，目前尚未确定有效的治疗形式。本文所综述的研究结果强烈表明，基底神经节异常总体上参与了精神综合征的病理生理学过程，尤其是精神分裂症。
