Seckl M J, Newlands E S
Gestational Trophoblastic Disease Centre, Department of Medical Oncology, Charing Cross Hospital, London, UK.
Gen Diagn Pathol. 1997 Nov;143(2-3):159-71.
Gestational trophoblastic disease (GTD) forms a spectrum of illness from the borderline malignancy of hydatidiform mole to the highly aggressive behaviour of choriocarcinoma. In the past, many women have died from this group of disorders. However, during the last 45 years highly effective chemotherapy regimens have been developed which can be appropriately tailored to the individual patient's risk of becoming resistant to the treatment. As a result, the management of GTD is one of the modern success stories in oncology. Today, with an integrated approach to management few women die from their trophoblastic tumours.
妊娠滋养细胞疾病（GTD）涵盖了从葡萄胎的交界性恶性肿瘤到绒毛膜癌的高度侵袭性行为等一系列病症。过去，许多女性死于这类疾病。然而，在过去的45年里，已经开发出了高效的化疗方案，这些方案可以根据个体患者对治疗产生耐药性的风险进行适当调整。因此，GTD的管理是肿瘤学领域现代成功案例之一。如今，采用综合管理方法，很少有女性死于滋养细胞肿瘤。
