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孟加拉国人和动物弓形虫感染的血清流行病学研究。

Sero-epidemiological studies on Toxoplasma gondii infection in man and animals in Bangladesh.

作者信息

Samad M A, Dey B C, Chowdhury N S, Akhtar S, Khan M R

机构信息

Department of Medicine, Bangladesh Agricultural University, Mymensigh, Bangladesh.

出版信息

Southeast Asian J Trop Med Public Health. 1997 Jun;28(2):339-43.

PMID:9444017
Abstract

Sera from randomly selected 49 professional blood donors, 617 pregnant women, 14 butchers, 528 slaughtered goats and 24 domestic cats in the district of Mymensingh were tested for the presence of T. gondii antibodies using a Latex agglutination test (LAT). Overall 12.4% blood donors, 11.18% pregnant women, 50.00% butchers, 12.88% slaughtered goats and 33.33% cats had diagnostically significant antibody titers (> or = 1:64) to T. gondii. Epidemiological studies on T. gondii infection with LAT were conducted in 25 family members with sero-positive cats and 9 family members with 2 sero-positive women without cats in the family. Significantly (p < 0.01) higher sero-positivity rate was recorded in the family members (24.00%) with positive cats in comparison to family members (11.11%) without cats. The epidemiologic study indicates that infected cats and goat meat might be significant sources of T. gondii infection for humans in Bangladesh.

摘要

在迈门辛地区,对随机选取的49名职业献血者、617名孕妇、14名屠夫、528只屠宰山羊和24只家猫的血清进行了乳胶凝集试验(LAT),以检测是否存在弓形虫抗体。总体而言,12.4%的献血者、11.18%的孕妇、50.00%的屠夫、12.88%的屠宰山羊和33.33%的猫对弓形虫具有诊断意义的抗体滴度(≥1:64)。对25名家中有血清学阳性猫的家庭成员和9名家中有2名血清学阳性女性但无猫的家庭成员进行了关于弓形虫感染的流行病学研究,采用乳胶凝集试验。与没有猫的家庭成员(11.11%)相比,家中有阳性猫的家庭成员(24.00%)的血清阳性率显著更高(p<0.01)。流行病学研究表明,受感染的猫和山羊肉可能是孟加拉国人类弓形虫感染的重要来源。

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