氯丙嗪对人类回避和逃避反应的影响。
Effects of chlorpromazine on avoidance and escape responding in humans.
作者信息
Fischman M W, Smith R C, Schuster C R
出版信息
Pharmacol Biochem Behav. 1976 Jan;4(1):111-4. doi: 10.1016/0091-3057(76)90184-2.
PMID:944449
Abstract
The effects of chlorpromazine on shock avoidance and escape responding were determined using four human subjects lever pressing on a modified free operant avoidance schedule. Doses of chlorpromazine ranging from 50 to 100 mg and shock levels ranging from 0.35 to 3.0 mA were used. In general, the results showed that chlorpromazine suppressed avoidance responding at doses which did not suppress escape responding.
摘要
使用四名人类受试者，在改良的自由操作回避程序上进行杠杆按压，以确定氯丙嗪对回避电击和逃避反应的影响。使用了50至100毫克的氯丙嗪剂量以及0.35至3.0毫安的电击强度。总体而言，结果表明，氯丙嗪在不抑制逃避反应的剂量下抑制了回避反应。
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