Commun Dis Intell. 1997 Dec 25;21(23):349-53. doi: 10.33321/cdi.1997.21.60.
The World Health Organization (WHO) Western Pacific Region Gonococcal Antimicrobial Surveillance Programme is a multicentric long term programme for continuous surveillance of the antimicrobial susceptibility of Neisseria gonorrhoeae. In 1996 the programme examined the susceptibility of 8,421 isolates of gonococci to various antimicrobials in 17 focal points. A trend toward increased resistance noted in earlier years continued. The proportion of quinolone resistant gonococci reported from most centres either remained stable or increased. More than 50% of isolates in Hong Kong, China, Korea, Cambodia and the Philippines had altered quinolone susceptibility. Resistance to the penicillins was again widespread, and chromosomal mediated resistance was of increasing importance. Penicillinase producing Neisseria gonorrhoea were present in all but one centre. All isolates were sensitive to the third generation cephalosporins and only a very few isolates were spectinomycin resistant. A high proportion of isolates in a number of centres had high level tetracycline resistance, but the proportion of tetracycline resistant Neisseria gonorrhoea in most centres was less than 10%.
世界卫生组织（WHO）西太平洋区域淋球菌抗菌药物监测项目是一项多中心长期项目，旨在持续监测淋病奈瑟菌的抗菌药物敏感性。1996年，该项目在17个重点地区检测了8421株淋球菌对各种抗菌药物的敏感性。早年出现的耐药性增加趋势仍在持续。大多数中心报告的喹诺酮耐药淋球菌比例要么保持稳定，要么有所增加。在中国香港、韩国、柬埔寨和菲律宾，超过50%的分离株对喹诺酮的敏感性发生了改变。对青霉素的耐药性再次广泛存在，且染色体介导的耐药性日益重要。除一个中心外，所有中心均存在产青霉素酶的淋病奈瑟菌。所有分离株对第三代头孢菌素敏感，只有极少数分离株对壮观霉素耐药。许多中心的分离株中有很大比例对四环素高度耐药，但大多数中心的四环素耐药淋病奈瑟菌比例低于10%。
