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药物性胆固醇控制对公共卫生资源利用的影响——斯堪的纳维亚辛伐他汀生存研究(4-S研究)对瑞士健康管理条件下成本控制的意义

[Effect of medicamentous cholesterol control on resources utilization in public health--significance of the Scandinavian Simvastatin Survival Study (4-S Study) for cost control in Swiss health management conditions].

作者信息

Szucs T D, Lüscher T F, Gutzwiller F

机构信息

Zentrum für Pharmakoökonomie, Universität Mailand.

出版信息

Schweiz Med Wochenschr. 1997 Nov 1;127(44):1819-23.

PMID:9446200
Abstract

Upward spiralling health care expenditures have triggered the need to assess the cost-effectiveness of medical interventions. Specifically, interventions in primary and secondary prevention represent an important field of research. A resource utilization analysis was performed on the basis of the recently published Scandinavian Simvastatin Survival Study. It could be shown that treatment with simvastatin compared to placebo leads to a reduction in patient costs of CHF 8.4 million. This represents a reduction of CHF 3770.- per patient. The effective daily treatment costs can thus be calculated at CHF 1.11, which is equivalent to 36% of the actual acquisition cost per day. These results support the notion that secondary coronary prevention is not only justified from a clinical but also from an economic point of view.

摘要

不断攀升的医疗保健支出引发了对评估医疗干预措施成本效益的需求。具体而言,一级和二级预防干预是一个重要的研究领域。基于最近发表的斯堪的纳维亚辛伐他汀生存研究进行了资源利用分析。结果表明,与安慰剂相比,辛伐他汀治疗可使患者成本降低840万瑞士法郎。这意味着每位患者成本降低3770瑞士法郎。因此,每日有效治疗成本可计算为1.11瑞士法郎,相当于每日实际采购成本的36%。这些结果支持了这样一种观点,即二级冠状动脉预防不仅从临床角度来看是合理的,从经济角度来看也是合理的。

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