Califf R M
Duke Clinical Research Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27705, USA.
Eur Heart J. 1997 Dec;18 Suppl F:F2-10. doi: 10.1093/eurheartj/18.suppl_f.2.
The GUSTO trials have provided continuing insight into the complexities of a simple fundamental relationship: early and sustained coronary perfusion in patients with acute myocardial infarction leads to lower mortality and morbidity. To a large extent, the GUSTO trials have attempted to develop approaches to therapy that will ensure the highest early rate of reperfusion with the least risk. A table provides a summary of the completed trials and those that are planned in attempts to provide further knowledge in the continuing quest to improve the plight of patients with acute myocardial infarction.
全球急性冠状动脉综合征治疗策略研究（GUSTO）试验持续深入探究了一个简单基本关系的复杂性：急性心肌梗死患者早期且持续的冠状动脉灌注可降低死亡率和发病率。在很大程度上，GUSTO试验试图开发治疗方法，以确保在风险最小的情况下实现最高的早期再灌注率。一张表格总结了已完成的试验以及计划开展的试验，旨在通过不断探索为改善急性心肌梗死患者的困境提供更多知识。
