Worth L T, Reef V B
Department of Clinical Studies, University of Pennsylvania, New Bolton Center, Kennett Square 19348, USA.
J Am Vet Med Assoc. 1998 Jan 15;212(2):248-53.
To determine clinical signs of pericarditis in horses and to determine whether there were any relationships among clinical signs, echocardiographic findings, treatment, and outcome.
Retrospective study.
18 horses.
Physical examination was performed on 16 horses. Cardiovascular abnormalities included tachycardia (n = 16), pericardial friction rub (10), venous distention (7), murmur (7), muffled heart sounds (6), weak arterial pulse (6), jugular pulse (6), and edema (5). Twelve horses also had respiratory abnormalities; the most common was dull lung sounds, ventrally, suggestive of pleural effusion (10). Echocardiography was the most important tool for diagnosis of pericarditis. Detection of clinical signs of right-sided heart failure was significantly associated with severe accumulation of pericardial effusion and with detection of cardiac compromise. Severe accumulation of pericardial effusion was also significantly associated with echocardiographic detection of cardiac compromise. Pericarditis was idiopathic in 6 horses, and bacterial in 5. Five horses had nonseptic pericarditis associated with bacterial respiratory disease, and 2 had nonseptic pericarditis associated with viral respiratory disease. Fourteen of the 18 horses were treated specifically for pericarditis; 10 received antimicrobials and 6 with suspected immune-mediated pericarditis received corticosteroids. Pericardial drainage and lavage were performed on 6 horses in which pericardial effusion or fibrin accumulation was compromising cardiac function. Pericarditis resolved in all 14 horses that were treated, and all 14 returned to their prior intended use.
With early detection of disease and aggressive treatment, the prognosis for horses with pericarditis is good.
确定马心包炎的临床体征,并确定临床体征、超声心动图检查结果、治疗方法及预后之间是否存在任何关联。
回顾性研究。
18匹马。
对16匹马进行了体格检查。心血管异常包括心动过速(n = 16)、心包摩擦音(10例)、静脉扩张(7例)、杂音(7例)、心音低沉(6例)、动脉搏动微弱(6例)、颈静脉搏动(6例)和水肿(5例)。12匹马还存在呼吸异常;最常见的是腹侧肺音减弱,提示胸腔积液(10例)。超声心动图是诊断心包炎最重要的工具。右侧心力衰竭临床体征的检测与心包积液的严重积聚及心脏功能受损的检测显著相关。心包积液的严重积聚也与超声心动图检测到的心脏功能受损显著相关。6匹马的心包炎为特发性,5匹马为细菌性。5匹马患有与细菌性呼吸道疾病相关的非感染性心包炎,2匹马患有与病毒性呼吸道疾病相关的非感染性心包炎。18匹马中有14匹接受了心包炎的特异性治疗;10匹接受了抗菌药物治疗,6匹疑似免疫介导性心包炎的马接受了皮质类固醇治疗。对6例心包积液或纤维蛋白积聚影响心脏功能的马进行了心包引流和灌洗。所有14例接受治疗的马的心包炎均得到缓解,所有14匹马均恢复到先前的预期用途。
早期发现疾病并积极治疗,马心包炎的预后良好。