Neumark Y D, Anthony J C
Johns Hopkins University, School of Hygiene and Public Health, Department of Mental Hygiene, Baltimore, MD 21205, USA.
Drug Alcohol Depend. 1997 Dec 15;48(3):193-7. doi: 10.1016/s0376-8716(97)00125-7.
This investigation examined the association between misbehavior in early life and subsequent injecting drug use (IDU) among Baltimore participants in the NIMH Epidemiologic Catchment Area study. Information about early misbehavior was collected in 1981 and about IDU in 1994-1996. Conditional logistic regression models were used to estimate the degree of association between early misbehavior and IDU, with injecting drug users (n = 38) and controls matched on census tract of residence (n = 745), selected from within the same community survey sample, and assessed in a methodologically identical manner. Early misbehavior was associated with subsequent IDU, independent of the associations with sex, age, and race. The estimated risk of IDU increased with the number of reported conduct problems. Early misbehavior also discriminated between injecting drug users and non-injecting drug users. These results, which support and extend earlier findings, have public health implications for preventing and stopping the risk-laden practice of injecting drug use.
本调查在国立精神卫生研究所流行病学集水区研究中的巴尔的摩参与者中，考察了早年行为不端与随后注射吸毒之间的关联。关于早年行为不端的信息于1981年收集，关于注射吸毒的信息于1994 - 1996年收集。条件逻辑回归模型用于估计早年行为不端与注射吸毒之间的关联程度，注射吸毒者（n = 38）和按居住普查区匹配的对照组（n = 745），从同一社区调查样本中选取，并以方法上相同的方式进行评估。早年行为不端与随后的注射吸毒相关，独立于与性别、年龄和种族的关联。注射吸毒的估计风险随着报告的行为问题数量增加而上升。早年行为不端也能区分注射吸毒者和非注射吸毒者。这些结果支持并扩展了早期发现，对预防和停止有风险的注射吸毒行为具有公共卫生意义。
