Rivera Del Rio J R, Flores R, Meléndez J, Gómez M A, Vila S, Hunter R
Internal Medicine Department, Universidad Central del Caribe, Hospital Regional Ramón Ruiz Arnau, Bayamón, Puerto Rico 00960-6032, USA.
Cell Mol Biol (Noisy-le-grand). 1997 Nov;43(7):1153-60.
Bacterial endocarditis (BE) is a serious medical condition seen in the injecting drug users (IDU) with or without HIV. Studies report a low prevalence of BE in HIV/AIDS patients and the clinical manifestations have been considered non-specific making early diagnosis difficult. The HIV Registry in our Center has recruited 1500 HIV/AIDS cases since May 1992. We decided to review and compare the clinical and epidemiological variables of patients admitted to the Registry with BE (23 pts) and without. Fever, sweats and weight loss were seen most frequent in BE patients as well as meningitis and pneumonia. The majority of the patients were IDU. Staphylococcus aureus was the most common pathogen. The tricuspid valve was the most affected valve. Mild insufficiency was the rule. The mortality in BE patients was higher than in the total group. The triad of IDU, the described constitutional signs and symptoms and coexisting meningitis and/or pneumonia, in the HIV/AIDS patient, should alert the physician to the presence of BE particularly in the outpatient setting were a more aggressive diagnostic approach should probably be attempted.
细菌性心内膜炎（BE）是一种在注射吸毒者（IDU）中出现的严重病症，无论其是否感染艾滋病毒。研究报告显示，艾滋病毒/艾滋病患者中BE的患病率较低，且临床表现被认为不具有特异性，这使得早期诊断变得困难。自1992年5月以来，我们中心的艾滋病毒登记处已招募了1500例艾滋病毒/艾滋病病例。我们决定回顾并比较登记处中患有BE（23例）和未患BE的患者的临床和流行病学变量。发热、盗汗和体重减轻在BE患者中最为常见，脑膜炎和肺炎也是如此。大多数患者为注射吸毒者。金黄色葡萄球菌是最常见的病原体。三尖瓣是受影响最严重的瓣膜。轻度关闭不全是常见情况。BE患者的死亡率高于总体组。在艾滋病毒/艾滋病患者中，注射吸毒、所述的全身症状以及并存的脑膜炎和/或肺炎，应提醒医生注意BE的存在，特别是在门诊环境中，可能应尝试采取更积极的诊断方法。
