Heffernan R, Henning K, Labowitz A, Hjelte A, Layton M
New York City Department of Health, New York, USA.
Emerg Infect Dis. 1998 Jan-Mar;4(1):113-6. doi: 10.3201/eid0401.980116.
Wide geographic variation in the prevalence of drug-resistant Streptococcus pneumoniae demonstrates the importance of tracking antimicrobial resistance locally. This survey of hospital microbiology laboratories in New York City found that penicillin resistance (MIC > or = 2.0 micrograms/ml) increased from 1.5% of S. pneumoniae isolates in 1993 to 6.3% in 1995 and that in 1995, one-third of isolates nonsusceptible to penicillin (MIC > or = 0.1 microgram/ml) were also nonsusceptible to an extended-spectrum cephalosporin (MIC > or = 1 microgram/ml).
耐药性肺炎链球菌患病率存在广泛的地域差异,这表明在当地追踪抗菌药物耐药性具有重要意义。这项对纽约市医院微生物实验室的调查发现,青霉素耐药性(最低抑菌浓度[MIC]≥2.0微克/毫升)在1993年占肺炎链球菌分离株的1.5%,到1995年升至6.3%,并且在1995年,三分之一对青霉素不敏感(MIC≥0.1微克/毫升)的分离株对广谱头孢菌素也不敏感(MIC≥1微克/毫升)。