Ciantar M
Department of Dental Surgery, University of Malta, Medical School, G'Mangia.
Dent Update. 1996 Nov;23(9):374-7.
Gingival overgrowth is a well-known side-effect of nifedipine therapy. The altered gingival architecture can be disfiguring, aesthetically displeasing and cause discomfort during mastication. Traditional treatment is based on surgical resection of the overgrown tissue followed by maintenance therapy aimed at achieving a high standard of plaque control. This case report describes the non-surgical management of a patient presenting with nifedipine-induced gingival overgrowth. Establishment and maintenance of a considerably improved standard of plaque control led to complete resolution of the overgrowth without recurrence, even though the medication dose was increased. The possible pathogenesis of nifedipine-induced gingival overgrowth is considered and the all-important role of plaque control emphasized.
牙龈增生是硝苯地平治疗众所周知的副作用。牙龈结构改变会影响美观,令人不悦,且在咀嚼时会引起不适。传统治疗方法是手术切除增生组织,随后进行维持治疗,旨在实现高标准的菌斑控制。本病例报告描述了一名硝苯地平引起牙龈增生患者的非手术治疗。即使增加了药物剂量,但通过建立并维持显著改善的菌斑控制标准,牙龈增生完全消退且未复发。文中探讨了硝苯地平引起牙龈增生可能的发病机制,并强调了菌斑控制的至关重要作用。