Berner R, Heinen F, Pelz K, van Velthoven V, Sauer M, Korinthenberg R
Department of Pediatrics, University Hospital of Freiburg, Germany.
Neuropediatrics. 1997 Dec;28(6):333-4. doi: 10.1055/s-2007-973726.
Non-anthrax Bacillus species are usually considered to be contaminants if found in clinical specimens. Only a few patients with systemic infections due to Bacillus cereus are reported. We present the case of a 18-month old boy with a primitive neuroectodermal tumor (PNET) in the brainstem and obstructive hydrocephalus that required an outlying and subsequently a ventriculoperitoneal drain. Following contamination at the site of entry of the external drain, shunt infection and meningitis with Bacillus cereus developed. Antibiotic treatment with vancomycin failed to eliminate the bacterium from the cerebrospinal fluid, so the shunt system had to be removed. Explantation of the shunt and addition of fosfomycin to the antibiotic regimen resulted in a complete cure of the infection.
非炭疽芽孢杆菌属物种如果在临床标本中被发现，通常被认为是污染物。仅有少数蜡样芽孢杆菌引起全身感染的患者被报道。我们报告了一名18个月大男孩的病例，其脑干有原始神经外胚层肿瘤（PNET）并伴有梗阻性脑积水，需要先进行外置引流，随后进行脑室腹腔分流术。在外置引流管入口处发生污染后，出现了蜡样芽孢杆菌引起的分流感染和脑膜炎。用万古霉素进行抗生素治疗未能从脑脊液中清除该细菌，因此不得不移除分流系统。移除分流装置并在抗生素治疗方案中添加磷霉素后，感染得以完全治愈。
