Yilmaz Emel, Ozakin Cüneyt, Sinirtaş Melda, Evci Canan, Akalin Halis, Gedikoğlu Suna
Uludağ Universitesi Tip Fakültesi, Enfeksiyon Hastaliklari ve Klinik Mikrobiyoloji Anabilim Dali, Bursa.
Mikrobiyol Bul. 2006 Jan-Apr;40(1-2):99-102.
Oerskovia species are Nocardia-like bacteria that have been only and rarely associated with human infections. In this report, a meningitis case caused by Oerskovia xanthineolytica was presented. A 44 years old male patient who had experienced ventriculo-peritoneal shunt (V-P shunt) due to hydrocephaly, developed meningitis. O. xanthineolytica was isolated from three of the cerebrospinal fluid (CSF) samples and V-P shunt cultures. Identification of the isolate was performed by Phoenix SystemTM (NMIC/ID-5 panel, Becton Dickson, Sparks, MD, USA). Empirical vancomycin (2x1 g/day iv) plus rifampin (1x600 mg/day po) therapy has failured. Since CSF cultures were still positive in the 22nd day of therapy, the shunt was removed and continuation of the same antimicrobial treatment for 42 days resulted in complete cure.
厄氏菌属是一类类似诺卡氏菌的细菌，仅偶尔与人类感染相关。在本报告中，呈现了一例由解黄嘌呤厄氏菌引起的脑膜炎病例。一名44岁男性患者因脑积水接受了脑室-腹腔分流术（V-P分流术），随后发生了脑膜炎。从三份脑脊液（CSF）样本和V-P分流培养物中分离出了解黄嘌呤厄氏菌。通过Phoenix SystemTM（NMIC/ID-5鉴定板，美国马里兰州斯帕克斯市贝克顿·迪金森公司）对分离株进行鉴定。经验性使用万古霉素（静脉注射，每日2次，每次1克）加利福平（口服，每日1次，每次600毫克）治疗失败。由于在治疗第22天时脑脊液培养仍为阳性，遂移除分流管，并继续使用相同抗菌治疗42天，最终实现完全治愈。
