戈谢病：骨骼受累情况评估及酶替代治疗反应

Gaucher disease: assessment of skeletal involvement and therapeutic responses to enzyme replacement.

作者信息

Hermann G, Pastores G M, Abdelwahab I F, Lorberboym A M

机构信息

Radiology Department, Mount Sinai Medical Center, New York, NY 10029, USA.

出版信息

Skeletal Radiol. 1997 Dec;26(12):687-96. doi: 10.1007/s002560050313.

DOI:10.1007/s002560050313

PMID:9453101

Abstract

The clinical, pathological and radiological manifestations of type 1 Gaucher disease and the role of imaging techniques such as CT, MRI and sulfur-colloid scintigraphy in the management of these patients is discussed. MRI appears to be the most valuable imaging technique for evaluating bone marrow involvement and detecting disease activity. MRI is also useful in assessing therapeutic responses to enzyme replacement therapy.

摘要

本文讨论了1型戈谢病的临床、病理和放射学表现，以及CT、MRI和硫胶体闪烁扫描等成像技术在这些患者管理中的作用。MRI似乎是评估骨髓受累情况和检测疾病活动最有价值的成像技术。MRI在评估酶替代疗法的治疗反应方面也很有用。