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一名患有先天性肾上腺皮质增生症的女性两性畸形患者的垂体-性腺功能

Pituitary-gonadal function in a female hermaphrodite with congenital adrenal hyperplasia.

作者信息

Ishida H, Kukutani K, Imao S, Hirose K, Isurugi K

出版信息

J Urol. 1976 Jul;116(1):130-1. doi: 10.1016/s0022-5347(17)58714-5.

Abstract

A case of a 31-year-old female hermaphrodite with congenital adrenal hyperplasia is reported and some endocrinological studies are presented. After the administration of dexamethasone, the elevated levels of serum testosterone were suppressed, while the lower levels of serum luteinizing hormone and follicle stimulating hormone were elevated. Since the virilization was too developed to change the sex role, the patient remained as a male subject without cortisol replacement therapy and underwent a plastic operation to construct the penile urethra.

摘要

报告了一例31岁先天性肾上腺皮质增生的女性假两性畸形病例,并展示了一些内分泌学研究结果。给予地塞米松后,血清睾酮水平升高得到抑制,而血清促黄体生成素和促卵泡生成素较低水平则升高。由于男性化程度过高无法改变性别角色,该患者在未进行皮质醇替代治疗的情况下仍保持男性身份,并接受了阴茎尿道成形整形手术。

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