[缺糖转铁蛋白在酒精相关问题中的作用]
[Usefulness of carbohydrate-deficient transferrin in alcohol-elated problems].
作者信息
Rubio Valladolid G, Martínez Ruiz M
机构信息
Departamento de Psiquiatría, Universidad Autónoma, Madrid.
出版信息
An Med Interna. 1997 Sep;14(9):473-7.
BACKGROUND
Carbohydrate-Deficient Transferrin (CDT) is a new marker for excessive alcohol drinking. It appears to be useful to detect alcoholism, harmful consumption and relapse. It have been introduced in our country recently.
METHOD
Recent studies about utility of CDT have been reviewed.
RESULTS
Sensitivity and specificity of CDT level as a marker of alcoholism were 72-97% and 31-81% respectively. As a marker of harmful consumption its sensitivity was 15-69% and its sensitivity was higher than 82%. CDT was demonstrated to be a effective maker for evaluating alcoholic abstinence in alcoholic patients.
CONCLUSIONS
CDT determinations have a high specificity for screening heavy drinking in different settings. Problems related to its sensitivity are discussed.
背景
缺糖转铁蛋白（CDT）是过量饮酒的一种新标志物。它似乎对检测酒精中毒、有害饮酒及复发情况很有用。它最近已被引入我国。
方法
对近期有关CDT效用的研究进行了综述。
结果
CDT水平作为酒精中毒标志物的敏感性和特异性分别为72% - 97%和31% - 81%。作为有害饮酒的标志物，其敏感性为15% - 69%，特异性高于82%。CDT被证明是评估酒精性患者戒酒情况的有效标志物。
结论
CDT测定在不同环境下筛查重度饮酒具有高特异性。讨论了与其敏感性相关的问题。
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