Yokomichi H, Kondo Y, Tanaka T
Nihon Heikatsukin Gakkai Zasshi. 1976 Mar;12(1):15-24. doi: 10.1540/jsmr1965.12.15.
Alterations in the electrical activity of the stomach were studied in 40 unanesthetized dogs with intact vagal innervation, with selective proximal vagotomy (SPV) and with truncal vagotomy (TV) using a chronically implanted unipolar needle electrodes. The basic electrical rhythm (BER) of the normal canine stomach occurred regularly in the frequency of 4.5 to 5.5 cycles per minutes with a waxing and waning of initial and second potentials repeated in every 5 to 6 minutes. After SPV, irregular BER was observed occasionally within a few days postoperatively. After TV, irregularity of BER was more marked and frequent for the first 2 weeks. Subcutaneous administration of bethanechol chloride or histamine decreased the frequency of regular BER and increased the magnitude of second potentials equally in any dog of the control, SPV and TV groups. Similar changes were observed after feeding of the canned meat. Insulin-induced hypoglycemia increased the magnitude of antral second potentials in either control or SPV dogs. In contrast, TV dogs revealed repetition of initial potentials shortly after intravenous adminstration of insulin, but failed to show any changes relevant to hypoglycemia.
使用慢性植入的单极针电极，对40只迷走神经完整、接受选择性近端迷走神经切断术（SPV）和迷走神经干切断术（TV）的未麻醉犬的胃电活动变化进行了研究。正常犬胃的基本电节律（BER）以每分钟4.5至5.5次的频率有规律地出现，初始电位和第二电位的强弱变化每5至6分钟重复一次。SPV术后数天内偶尔观察到不规则的BER。TV术后，BER的不规则性在前2周更为明显和频繁。皮下注射氯化氨甲酰甲胆碱或组胺可同等程度地降低对照组、SPV组和TV组任何犬的正常BER频率，并增加第二电位的幅度。喂食罐装肉后也观察到类似变化。胰岛素诱导的低血糖可增加对照组或SPV犬胃窦第二电位的幅度。相比之下，TV犬在静脉注射胰岛素后不久出现初始电位重复，但未显示与低血糖相关的任何变化。
