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[脂肪酸酰胺对胶束中磷脂酶A2催化的磷脂酰胆碱水解的影响]

[Effects of fatty acid amides on phosphatidylcholine hydrolysis catalyzed by phospholipase A2 in micelles].

作者信息

Andreiuk G M, Kisel' M A, Litvinko N M

出版信息

Ukr Biokhim Zh (1978). 1997 Jan-Feb;69(1):32-6.

PMID:9454375
Abstract

The effect of fatty acid amides on the hydrolysis of natural phosphatidylcholine and its semisynthetic analog, dioleoyl phosphatidylcholine, catalyzed by phospholipase A2 in mixed micelles with Triton X-100 has been studied. Palmitoylamide, oleoylamide, and stearoylamide were shown to be the inhibitors of enzymatic phospholipid hydrolysis.

摘要

研究了脂肪酸酰胺对磷脂酶A2在与 Triton X-100形成的混合胶束中催化天然磷脂酰胆碱及其半合成类似物二油酰磷脂酰胆碱水解的影响。结果表明,棕榈酰胺、油酰胺和硬脂酰胺是酶促磷脂水解的抑制剂。

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Pancreatic phospholipase A2 hydrolysis of phosphatidylcholines in various physicochemical states.
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