• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities.

作者信息

Lyman S D, Jacobsen S E

机构信息

Department of Molecular Genetics, Immunex Corp, Seattle, WA 98101, USA.

出版信息

Blood. 1998 Feb 15;91(4):1101-34.

PMID:9454740
Abstract
摘要

相似文献

1
c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities.c-kit配体和Flt3配体：具有重叠但不同活性的干/祖细胞因子。
Blood. 1998 Feb 15;91(4):1101-34.
2
Biology of flt3 ligand and receptor.Flt3配体与受体的生物学特性
Int J Hematol. 1995 Aug;62(2):63-73. doi: 10.1016/0925-5710(95)00389-a.
3
Human CD34+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells.能够在NOD/SCID小鼠中进行多谱系植入的人类CD34+造血干细胞表达flt3：小鼠和候选人类造血干细胞上flt3和c-kit的表达及反应模式不同。
Blood. 2003 Aug 1;102(3):881-6. doi: 10.1182/blood-2002-06-1694. Epub 2003 Apr 3.
4
Flt3/Flk-2 and c-Kit are not essential for the proliferation of B lymphoid progenitor cells in the bone marrow of the adult mouse.Flt3/Flk-2和c-Kit对于成年小鼠骨髓中B淋巴细胞祖细胞的增殖并非必需。
Exp Hematol. 1998 Jun;26(6):478-88.
5
The flt3 ligand: a hematopoietic stem cell factor whose activities are distinct from steel factor.Flt3配体：一种造血干细胞因子，其活性与Steel因子不同。
Stem Cells. 1994;12 Suppl 1:99-107; discussion 108-10.
6
Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells.白血病细胞中FLT3受体的表达及对FLT3配体的反应。
Leukemia. 1996 Apr;10(4):588-99.
7
Stem cell factor and hematopoiesis.干细胞因子与造血作用
Blood. 1997 Aug 15;90(4):1345-64.
8
Lymphoid-restricted development from multipotent candidate murine stem cells: distinct and complimentary functions of the c-kit and flt3-ligands.多能候选小鼠干细胞的淋巴细胞限制性发育：c-kit和flt3配体的独特互补功能
Blood. 1999 Dec 1;94(11):3781-90.
9
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity.骨髓中Lin(-)Sca1(+)c-kit(+)干细胞区室中Flt3表达的上调伴随着自我更新能力的丧失。
Immunity. 2001 Oct;15(4):659-69. doi: 10.1016/s1074-7613(01)00220-5.
10
Role of the stem cell factor (SCF) receptor and the alternative forms of its ligand (SCF) in the induction of long-term growth by stroma cells.干细胞因子（SCF）受体及其配体（SCF）的不同形式在基质细胞诱导长期生长中的作用。
Leukemia. 1997 Apr;11 Suppl 3:493-5.

引用本文的文献

1
The use of autologous platelet-rich plasma in embryo culture to obtain high-quality embryos.在胚胎培养中使用自体富血小板血浆以获得高质量胚胎。
Sci Rep. 2025 Jul 18;15(1):26025. doi: 10.1038/s41598-025-07688-x.
2
Retrospective Safety Evaluation of Combined Chlorambucil and Toceranib for the Treatment of Different Solid Tumours in Dogs.苯丁酸氮芥与托西拉尼联合治疗犬不同实体瘤的回顾性安全性评估
Animals (Basel). 2024 Nov 26;14(23):3420. doi: 10.3390/ani14233420.
3
Pharmacokinetics, pharmacodynamics, and safety of GS-3583, a FLT3 agonist Fc fusion protein, from single-ascending-dose phase I study in healthy participants.
在健康参与者中进行的单递增剂量 I 期研究中，GS-3583（一种 FLT3 激动剂 Fc 融合蛋白）的药代动力学、药效学和安全性。
Clin Transl Sci. 2024 Aug;17(8):e70011. doi: 10.1111/cts.70011.
4
Precision medicine in AML: overcoming resistance.精准医学治疗 AML：克服耐药性。
Int J Hematol. 2024 Oct;120(4):439-454. doi: 10.1007/s12185-024-03827-8. Epub 2024 Aug 1.
5
Flt3 agonist enhances immunogenicity of arenavirus vector-based simian immunodeficiency virus vaccine in macaques.Flt3 激动剂增强基于沙粒病毒载体的猴免疫缺陷病毒疫苗在猕猴中的免疫原性。
J Virol. 2024 Jul 23;98(7):e0029424. doi: 10.1128/jvi.00294-24. Epub 2024 Jun 3.
6
High FLT3 expression increases immune-cell infiltration in the tumor microenvironment and correlates with prolonged disease-free survival in patients with non-small cell lung cancer.高 FLT3 表达增加肿瘤微环境中的免疫细胞浸润，并与非小细胞肺癌患者无病生存期延长相关。
Mol Oncol. 2024 May;18(5):1316-1326. doi: 10.1002/1878-0261.13597. Epub 2024 Feb 7.
7
Phase I Study of GS-3583, an FMS-like Tyrosine Kinase 3 Agonist Fc Fusion Protein, in Patients with Advanced Solid Tumors.FMS 样酪氨酸激酶 3 激动剂 Fc 融合蛋白 GS-3583 治疗晚期实体瘤患者的 I 期研究。
Clin Cancer Res. 2024 Jul 15;30(14):2954-2963. doi: 10.1158/1078-0432.CCR-23-2808.
8
Multiple intratumoral sources of kit ligand promote gastrointestinal stromal tumor.多个肿瘤内 kit 配体来源促进胃肠间质瘤。
Oncogene. 2023 Aug;42(34):2578-2588. doi: 10.1038/s41388-023-02777-5. Epub 2023 Jul 19.
9
Effects of an Intervention with Selenium and Coenzyme Q on Five Selected Age-Related Biomarkers in Elderly Swedes Low in Selenium: Results That Point to an Anti-Ageing Effect-A Sub-Analysis of a Previous Prospective Double-Blind Placebo-Controlled Randomised Clinical Trial.补充硒和辅酶 Q10 对低硒瑞典老年人 5 种与年龄相关生物标志物的影响：指向抗衰老作用的结果——一项先前前瞻性双盲安慰剂对照随机临床试验的亚分析。
Cells. 2023 Jul 4;12(13):1773. doi: 10.3390/cells12131773.
10
Generation of Red Blood Cells from Human Pluripotent Stem Cells-An Update.人多能干细胞生成红细胞：最新进展
Cells. 2023 Jun 5;12(11):1554. doi: 10.3390/cells12111554.