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[直肠癌的治疗——优化可能性]

[The treatment of rectal cancer--the optimizing possibilities].

作者信息

Chifan M, Dănilă N, Niculescu D, Târcoveanu E, Georgescu S, Epure O, Andronic D, Găleşanu M R, Carasevici E

机构信息

Clinica I-a Chirurgicală, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1996 Jan-Jun;100(1-2):94-8.

PMID:9455405
Abstract

The authors studies 280 rectal cancers treated in the first surgical clinic of Iaşi in the period 1981-1994. Although surgery is the main treatment of these tumors, it cannot be and it must be not used alone. Surgery must be associated with radio- and chemotherapy, because is the only way possible to increase the number of resections for rectal tumors and the survival rate. For the 263 tumors operated the resectability was 73, 5%: Milles's operation 101 (36, 7%), Dixon's operation 81 (30, 79%), other operation 91 (33, 11%). We consider that Dixon's operation is the best choice for the tumors in the stages A and B of Dukes classifications. Preoperative radiotherapy can influence the tumor volume (downstaging) and decrease local recurrences to about 10-15%. Surgery alone must be practiced only in emergencies. Postoperative chemotherapy is mandatory and it reduces local recurrences and delays metastasis evolution.

摘要

作者研究了1981年至1994年期间在雅西第一外科诊所治疗的280例直肠癌。虽然手术是这些肿瘤的主要治疗方法,但它不能也绝不能单独使用。手术必须与放疗和化疗相结合,因为这是增加直肠癌切除数量和提高生存率的唯一可行方法。在接受手术的263例肿瘤中,可切除率为73.5%:米勒斯手术101例(36.7%),狄克逊手术81例(30.79%),其他手术91例(33.11%)。我们认为狄克逊手术是杜克分类法A期和B期肿瘤的最佳选择。术前放疗可影响肿瘤体积(降期),并将局部复发率降低至约10% - 15%。仅在紧急情况下才应单独进行手术。术后化疗是必需的,它可减少局部复发并延缓转移进展。

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Rev Med Chir Soc Med Nat Iasi. 1996 Jan-Jun;100(1-2):94-8.
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