Dorobăţ C, Dorobăţ G
Spitalul Clinic de Boli Infecţioase, Iaşi.
Rev Med Chir Soc Med Nat Iasi. 1996 Jul-Dec;100(3-4):44-7.
MODS, a phenomenon observed in many critically ill patients, is the progressive failure of two or more organ system which results from nonspecific systemic responses to abnormal intravascular inflammation. It is triggered by a number of cellular humoral and biochemical mediators (more than 100). This article takes up the role of individual organ system dysfunction in the development of MODS. Cardiopulmonary, renal and hepatic responses to injury and infection and the relation of these responses to the subsequent development of MODS have been the subject of intense investigations; recently the gastrointestinal tract was identified as another target organ in such patients.
多器官功能障碍综合征（MODS）是在许多重症患者中观察到的一种现象，是两个或更多器官系统的进行性衰竭，它源于对异常血管内炎症的非特异性全身反应。它由多种细胞、体液和生化介质（超过100种）触发。本文探讨了各个器官系统功能障碍在MODS发生发展中的作用。心肺、肾脏和肝脏对损伤和感染的反应以及这些反应与随后MODS发生的关系一直是深入研究的主题；最近，胃肠道被确定为这类患者的另一个靶器官。
